Schwartz T and Kmiec EB (2007) Reduction of gene repair by selenomethionine with the use of single-stranded oligonucleotides. BMC Molecular Biology Jan 26;8:7.
Skogen M, Roth J, Parekh-Olmedo H and Kmiec EB (2006) Short G-rich oligonucleotides as a therapeutic for Huntingtons Disease (HD). BMC Neuroscience Oct 2;7:65.
Ferrara L and Kmiec EB (2006) Targeted gene repair activates Chk1 and Chk2 and stalls replication in corrected cells. DNA Repair (Amst). 2006 Apr 8;5(4):422-31. Epub 2006 Jan 18.
Schwartz T and Kmiec EB (2005) Using methyl methanesulfonate (MMS) to stimulate targeted gene repair activity in mammalian cells. Gene Therapy and Molecular Biology 9: 193-202.
Engstrom J and Kmiec EB (2005) Caffeine elevates and stabilizes gene repair efficiencies in mammalian cells. Gene Therapy and Molecular Biology 9: 445-456.
Drury M, Skogen M and Kmiec EB (2005) A tolerance of DNA heterology in the mammalian targeted gene repair reaction. Oligonucleotides 15(3):155-171.
Parekh-Olmedo H, Ferrara L and Kmiec EB (2005) Progress and Prospects: targeted gene repair. Gene Therapy 12, 639-646.
Brachman E and Kmiec EB (2005) Gene repair in mammalian cells is stimulated by the elongation of S phase and transient stalling of replication forks. DNA Repair 4, 445-457.
Hu Y, Parekh-Olmedo H, Drury M, Skogen M and Kmiec EB (2005) Reaction parameters of targeted gene repair in mammalian cells. Molecular Biotechnology 29, 197-210.
Drury M and Kmiec EB (2004) Double displacement loops (double d-loops) are a more active template for gene repair activity. Oligonucleotides 14(4), 274-286.
Luciana F, Kmiec EB (2004) Camptothecin enhances the frequency of oligonucleotide-directed gene repair in mammalian cells by inducing DNA damage and activating homologous recombination. Nucleic Acids Research. 32(17), 5239-5248.
Luciana F, Parekh-Olmedo H, Kmiec EB (2004) DNA damage increases the frequency of gene repair in mammalian cells. Experimental Cell Research. 300(1), 170-179.
Brachman E and Kmiec EB (2004) DNA replication impacts repair frequency and transcription strand bias in targeted nucleotide exchange. J. Cell Science. 117(17), 3867-3874.
Van Brabant A, Williams JK, Parekh-Olmedo H, and Kmiec EB (2004) Gene editing of a human gene in yeast artificial chromosomes using modified single-stranded DNA and dual targeting. The Pharmacogenomics Journal. 4, 175-183.
Liu L, Katie K. Maguire, and Kmiec EB (2004) Engineering the eukaryotic recombinase Rad51 increases the frequency of gene repair in vivo. Nucl. Acids Res. 32, 2093-2101.
Parekh-Olmedo H, Wang J, Gusella JF, and Kmiec EB (2003) Modified single-stranded DNA oligomers inhibit aggregate formation and toxicity of expanded polyglutamine. The Journal of Molecular Neuroscience. 24(2), 257-268.
Maguire K and Kmiec EB (2003) Enhancement of in vivo targeted nucleotide exchange by nonspecific, carrier DNA. Methods in Molecular Biology. 262(13), 209-219.
Rice MC, Heckman B, Liu Y, Kmiec EB (2003) Fluorescent detection and isolation of DNA variants using stabilized RecA-coated oligonucleotides. Genome Research14, 116-125.
Hu Y, Liu L, Kmiec EB (2003) Reduction of Htt inclusion formation in strains of Saccharomyces cerevisiae deficient in certain DNA repair functions: A statistical analyses of phenotype. Experimental Cell Research 291(1), 46-55.
Parekh-Olmedo H, Engstrom J, Kmiec EB (2003) The effect of hydroxyurea and trichostatin A on targeted nucleotide exchange in yeast and mammalian cells. New York Academy of Science 1002, 43-56.
Liu L, Parekh-Olmedo H, Kmiec EB (2003) Development and regulation of gene repair. Nature Reviews Genetics 4, 679-689.
Parekh-Olmedo H, Kmiec EB (2003) Targeted nucleotide exchange in the CAG repeat region of the human HD gene. Biochem. Biophys. Res. Com. 310, 2, 660-666.
Liu L, Hu Y, Usher M, Kmiec EB (2003) The nuclease activity of Saccharomyces cerevisiae Mre11 functions in targeted nucleotide alteration. Applied and Environmental Microbiology 69, 10, 6216-6224.
Kmiec EB (2003) Targeted gene repair in the arena. Journal of Clinical Investigation 112, 5, 632-636.
Brachman E, Kmiec EB (2003) Targeted nucleotide repair of cyc1 mutations in Saccharomyces cerevisiae directed by modified single-stranded DNA oligonucleotides. Genetics 163, 2, 527-538.
Gamper HB, Nulf CJ, Corey DR, Kmiec EB (2003) The synaptic complex of RecA protein participates in hybridization and inverse strand exchange reactions. Biochemistry 42, 2643-2655.
Tran ND, Liu X, Yan Z, Abbote D, Jiang Q, Kmiec EB, Sigmund CD, Engelhardt JF (2003) Efficiency of chimeraplast gene targeting by direct nuclear injection using a GFP recovery assay. Molecular Therapy 7, 2, 248-253.
Drury M, Kmiec EB (2003) DNA pairing is an important step in the process of targeted nucleotide exchange. Nucleic Acids Research 31, 3, 899-910.
Agarwal S, Gamper HB, Kmiec EB (2002) Multiple nucleotide replacement can be directed by modified single-stranded oligonucleotides in vitro and in vivo. Biomolecular Engineering 20, 1, 7-20.
Parekh-Olmedo H, Drury M, Kmiec EB (2002) Targeted nucleotide exchange in Saccharomyces cerevisiae directed by short oligonucleotides containing locked nucleic acids. Chemistry and Biology 9, 1073-1084.
Liu L, Cheng S, van Brabant A, Kmiec EB (2002) Rad51p and Rad54p, but not Rad52p, elevate gene repair in Saccharomyces cerevisiae directed by modified single-stranded oligonucleotide vectors. Nucleic Acids Research 30, 13, 2742-2750.
Liu L, Rice MC, Drury M, Cheng S, Gamper H, Kmiec EB (2002) Strand bias in targeted gene repair is influenced by transcriptional activity. Molecular and Cellular Biology 22, 11, 3852-3863.
Parekh-Olmedo H., Krainc D, Kmiec EB (2002) Targeted gene repair and its application to neurodegenerative disorders. Neuron 33: 495-498.
Drury M, Skogen M and Kmiec EB (2005) A tolerance of DNA heterology in the mammalian targeted gene repair reaction. Oligonucleotides 15(3):155-171.
Liu H, Agarwal S, Kmiec E, Davis BR (2002) Targeted beta-globin gene conversion in human hematopoietic CD34(+) and Lin(-)CD38(-) cells. Gene Therapy 9: 118-126.
Kmiec EB (2002) Toward the mechanism of chimera-directed gene repair. In: Encyclopedia of the Human Genome.
Liu L, Rice MC, Kmiec EB (2001) In vivo gene repair of point and frameshift mutations directed by chimeric RNA/DNA oligonucleotides and modified single-stranded oligonucleotides. Nucleic Acids Research 29 (20), 4238-4250.
Kmiec EB, Johnson C, May GD (2001) Chloroplast lysates support directed mutagenesis via modified DNA and chimeric RNA/DNA oligonucleotides. Plant Journal 27 (3), 267-274.
Rice MC, Bruner M, Czymmek K, Kmiec EB (2001) In vitro and in vivo nucleotide exchange directed by chimeric RNA/DNA oligonucleotides in Saccharomyces cerevisae. Molecular Microbiology 40 (4), 857-868.
Rice MC, Czymmek K, Kmiec EB (2001) The potential of nucleic acid repair in functional genomics. Nature Biotechnology 19 (4), 321-326.
Parekh-Olmedo H, Czymmek K, Kmiec EB (2001) Targeted gene repair in mammalian cells using chimeric RNA/DNA oligonucleotides and modified single-stranded vectors. Science's STKE 73 1-13.
Gamper HB, Hou YM, Kmiec EB (2000) Evidence for a four-strand exchange catalyzed by the RecA protein. Biochemistry 39 (49), 15272-15281.
Gamper HB, Parekh H, Rice MC, Bruner M, Youkey H, Kmiec EB (2000) The DNA strand of chimeric RNA/DNA oligonucleotides can direct gene repair/conversion activity in mammalian and plant cell-free extracts. Nucleic Acids Research 28 (21), 4332-4339.
